I don't believe I'm privy to any secrets, but I'll do my best not to leak information. My complaint is with additive models of liability. [In brief compute an

I don't believe I'm privy to any secrets, but I'll do my best not to leak information. My complaint is with additive models of liability. [In brief compute an independent relative risk for each SNP. To compute the risk of disease, take the log sum of the relative risks.] I haven't seen a model that can take into account epistatic effects.