You're almost never going to get perfect genetic discrimination in all-or-nothing fashion. The final figure is very interesting: the key SNPs that affect contr

You're almost never going to get perfect genetic discrimination in all-or-nothing fashion. The final figure is very interesting: the key SNPs that affect controller status are located near one another in 3-space in the HLA-B binding groove at a key site for antigen presentation. The fact that the genetics are all pointing to specific parts of the molecule in 3-space is extremely helpful.