It's worth noting that tobacco contains harmala alkaloids [1] which are monoamine oxidase inhibitors (MAOIs). So it's possible those who persist with smoking in

It's worth noting that tobacco contains harmala alkaloids [1] which are monoamine oxidase inhibitors (MAOIs). So it's possible those who persist with smoking in place of vaping or other nicotine delivery mechanisms might be doing so because they're (unknowingly) self-medicating for depression. [1] https://en.wikipedia.org/wiki/Harmala_alkaloid https://en.wikipedia.org/wiki/Harmala_alkaloid