I'm not sure what you're talking about. I used Homebrew quite successfully this past summer on 10.7.5 - the only problem was that a few formulae weren't availab

I'm not sure what you're talking about. I used Homebrew quite successfully this past summer on 10.7.5 - the only problem was that a few formulae weren't available for it. I've since upgraded that machine to El Capitan and Homebrew still works great and I haven't found anything that doesn't work, including CUDA.