If you're talking about the developer of the software? Potentially. As to third parties, this article goes into painstaking detail on how difficult it is to set

If you're talking about the developer of the software? Potentially. As to third parties, this article goes into painstaking detail on how difficult it is to set up fuzzing for closed source binaries. You need to understand a certain amount of "rules" around each API call, and while you can duplicate their normal usage, there's a certain amount of thought that has to go into it.