Yeah, I think that's a reasonable point. There's definitely a good point of lamp-post searching here, imo. The biggest challenge is that technologies like mass

Yeah, I think that's a reasonable point. There's definitely a good point of lamp-post searching here, imo. The biggest challenge is that technologies like mass spec can't get you a truly unbiased few of the tumor epi-nome, and so it's hard to really get a truly measurement of what fraction are from where (this is what they are trying to do here, but I think depth is still an issue). The viruses part is interesting too, but from a different angle: viral specific t-cells are found, in abundance in tumors, and it's believed that they aren't doing anything (i.e., they're bystanders) - https://www.ncbi.nlm.nih.gov/pubmed/29769722 https://www.ncbi.nlm.nih.gov/pubmed/29769722