At work, yes. DoH will leak corporate internal DNS and lead to the public resolvers getting null routed. At home, I block all the public resolvers on my route

At work, yes. DoH will leak corporate internal DNS and lead to the public resolvers getting null routed. At home, I block all the public resolvers on my router and intercept DNS, tunnel it through a vpn mesh. For most people at public open WiFi spots, DoH could certainly help.