3 ms·
In mice. (Just pointing out that, as useful as rodent studies are, this isn’t a result that can be generalized to people.)
by oliveshell 8y ago
In mice.
(Just pointing out that, as useful as rodent studies are, this isn’t a result that can be generalized to people.)
- NPMaxwell 8y agoHave you seen any tests of this with people? Or heard any first hand witnessing about ketamine and males? I hear it is considered a drug to take when going to clubs. Which reminds me of another quirky result: caffeine promotes wakefulness in fruit flies: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757164/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757164/ Without specific selective pressures, traits persist through species
- oliveshell 8y agoNo, but from the article you linked: “Gould doubts that the sex of the person administering the drug affects how well it works in a depressed patient, but it's never been tested.“ It seems to be related to stress response, which the mice were experiencing in the presence of male handlers. One would assume the same issue isn’t present in humans unless they become anxious and stressed when men are around. That said, it does have interesting implications for the drug’s relationship with stress; e.g., it might have stronger subjective effects in folks with high stress or stimulation levels at the time of administration.