3 ms·

You absolutely don’t need such caloric restriction to revert diabetes. All it takes is a very low carb or keto diet. Even without exercise.

toddh 8y ago
At that calorie level it's basically a fast mimicking diet, so part of the benefit would be autophagy and the respawning of stem cells. It's hard to tell how much that helps however.
- acangiano 8y ago
  That’s definitely a factor. That and the automatic reduction in carb intake with such a caloric restriction. I mean, if they fed them pure sugar, they’d still be getting “only” 200g of carbs per day which is still less than what a lot of people who developed diabetes used to eat. More realistically they are likely getting significantly less carbs per day with elements of fasting thrown in.
PerfectElement 8y ago
Or certain types of plant-based diets[1][2][3]. 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466941/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466941/ 2. https://www.omicsonline.org/open-access/diabetes-reversal-by-plantbased-diet-2167-0943-1000232-94442.html https://www.omicsonline.org/open-access/diabetes-reversal-by... 3. https://www.ncbi.nlm.nih.gov/pubmed/20425575 https://www.ncbi.nlm.nih.gov/pubmed/20425575
- jumanchiss 8y ago
  1. Vegan doctors Bernstein AM, Esselstyn, Barnard ND et al. (and of course the WHO) cherry-pick studies that support their theory. 2. 3-days study with only 55 patients 3. Questionable observational (selection bias) studies and more Neal D. Barnard.
onetimemanytime 8y ago
Problem is keeping it, as almost everyone can keep the diet for a few months. We all know what we should do but don't, sometimes until is too late. The person that invents a pill to trick our genes not to seek what was once rare (fat, sweets, carbs etc) will be a trillionaire. When our current genes were stamped "we" maybe had to hunt for days to eat once. Now we drive to McDonalds, order our or open the fridge door. Maybe something that puts our metabolism on steroids?
- acangiano 8y ago
  Right, but still significantly easier than staying on an 800 calorie diet.
- RugnirViking 8y ago
  Many drugs that put our metabolitism on steroids cause deaths from overheating - the energy has to go somewhere.

toddh 8y ago

At that calorie level it's basically a fast mimicking diet, so part of the benefit would be autophagy and the respawning of stem cells. It's hard to tell how much that helps however.

acangiano 8y ago
That’s definitely a factor. That and the automatic reduction in carb intake with such a caloric restriction. I mean, if they fed them pure sugar, they’d still be getting “only” 200g of carbs per day which is still less than what a lot of people who developed diabetes used to eat. More realistically they are likely getting significantly less carbs per day with elements of fasting thrown in.

PerfectElement 8y ago

Or certain types of plant-based diets[1][2][3]. 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466941/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466941/ 2. https://www.omicsonline.org/open-access/diabetes-reversal-by-plantbased-diet-2167-0943-1000232-94442.html https://www.omicsonline.org/open-access/diabetes-reversal-by... 3. https://www.ncbi.nlm.nih.gov/pubmed/20425575 https://www.ncbi.nlm.nih.gov/pubmed/20425575

jumanchiss 8y ago
1. Vegan doctors Bernstein AM, Esselstyn, Barnard ND et al. (and of course the WHO) cherry-pick studies that support their theory. 2. 3-days study with only 55 patients 3. Questionable observational (selection bias) studies and more Neal D. Barnard.

onetimemanytime 8y ago

Problem is keeping it, as almost everyone can keep the diet for a few months. We all know what we should do but don't, sometimes until is too late. The person that invents a pill to trick our genes not to seek what was once rare (fat, sweets, carbs etc) will be a trillionaire. When our current genes were stamped "we" maybe had to hunt for days to eat once. Now we drive to McDonalds, order our or open the fridge door. Maybe something that puts our metabolism on steroids?

acangiano 8y ago
Right, but still significantly easier than staying on an 800 calorie diet.
RugnirViking 8y ago
Many drugs that put our metabolitism on steroids cause deaths from overheating - the energy has to go somewhere.