A lot of designer drugs are synthesized in places like Israel, which has no law prohibiting drug analogs. Mephedrone started to become widely popularized in the

A lot of designer drugs are synthesized in places like Israel, which has no law prohibiting drug analogs. Mephedrone started to become widely popularized in the Middle East and Europe because of an Israeli manufacturer/online distributor. Quote from the pharma crime director of Israel's Ministry of Health: "Israel, to my sad dismay, is a major leader in designer drugs for this reason."