3 ms·
On the other hand, we can (today!) predict height from raw sequence with correlation 0.65: http://www.genetics.org/content/210/2/477 http://www.genetics.org/con
by sanxiyn 8y ago
On the other hand, we can (today!) predict height from raw sequence with correlation 0.65: http://www.genetics.org/content/210/2/477 http://www.genetics.org/content/210/2/477. It does not mean we can do such prediction for designed sequence (predictor likely will fail to generalize), but it can be used to select from natural variation. I don't see any wishful thinking here.
- jakobegger 8y agoYes, selecting the "tallest" embryo for implantation sounds somewhat feasible. It's similar to selective breeding with a shorter feedback loop. The only downside is that you are only selecting for genotype, instead of phenotype, so your model might accidentally select for some other things that you didn't expect. But that's very different from designing an embryo by direct genetic modification.
- blueblimp 8y agoAgreed, there's a big difference between what's possible with selection and what's possible with editing. Selection is already available (as increasingly sophisticated PGD). It's a lot trickier to do anything useful with editing.