I am aware of this. Genetic engineering implies far more power than Gwern mentions for one round of embryo selection. 5 standard deviations may sound a lot for

I am aware of this. Genetic engineering implies far more power than Gwern mentions for one round of embryo selection. 5 standard deviations may sound a lot for you, but in animal breeding we have changed the distribution of various traits by far more than 5 standard deviations. Into the dozens.