I use comprehensions because they're self-contained. Instead of a loop with a few statements that introduces new variables into the scope, there's a single expr

I use comprehensions because they're self-contained. Instead of a loop with a few statements that introduces new variables into the scope, there's a single expression with fewer loose ends. I think using (non-generator) comprehensions for efficiency is usually the wrong reason. I find the split comprehension more readable than the equivalent for loop. That's mostly because I'm used to that style, of course, but it's also because it's more constrained. Comprehensions have a very limited grammar, but there are multiple ways to write a for loop that builds a list.