I think there's a valid point: we're not totally free agents. There might be some chemicals that are too addictive. For example, the cigarette companies refin

I think there's a valid point: we're not totally free agents. There might be some chemicals that are too addictive. For example, the cigarette companies refined tobacco to make it more addictive, enslaving millions to an addictive carcinogen. Decriminalization of harder drugs might be a better method, since it partially removes profit motive for production and refinement but doesn't incentivize use.