4 ms·
My father had Factor V Leiden[1], a mutation that increases blood clotting. He was hospitalized multiple times in his 30s, and died suddenly at age 50. After hi
by thamer 8y ago
My father had Factor V Leiden[1], a mutation that increases blood clotting. He was hospitalized multiple times in his 30s, and died suddenly at age 50. After his first blood clot he was put on anti-coagulants and took them every day of his life.
There is a 50% chance to pass this mutation to your offspring, and I wanted to know whether I could be affected. I discovered that I did indeed inherit the same allele, and went to see a hematologist to discuss it. She advised that I not smoke and keep fit (unlike my father) and that I shouldn't worry about taking medication unless some evidence of blood clots appears. This was always a worry for me, not knowing whether I would suffer the same fate. When I sent my DNA to 23andme, I was 25 years old and wondering if I'd already lived half of my life. Getting the results and following up with a specialist gave me great relief and eliminated this worry pretty much entirely.
[1] https://en.wikipedia.org/wiki/Factor_V_Leiden https://en.wikipedia.org/wiki/Factor_V_Leiden
- ska 8y agoIs this not a test you could have got done a more conventional way?
- thamer 8y agoYes it is, and I did this test again on its own after seeing the hematologist. But 23andme offers much more, and when I saw that they offered 50% off on DNA day I impulsively bought it.
- moonka 8y agoNot sure if this is why, but I know some folks who are concerned about getting such tests done at the doctor's office due to both cost, and the fact that it will go into their medical records (and thus possibly impact insurance).