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Exactly. Look at the computational power we have thrown into figuring out just how a protein folds for example. I worked in a lab where we used a lot of inferen
by johnwyles 8y ago
Exactly. Look at the computational power we have thrown into figuring out just how a protein folds for example. I worked in a lab where we used a lot of inference in the 2D structure of RNA over a decade ago after the 23s and 16s ribosomes tertiary structures were resolved. I was simply working with 70-120 base-pair tRNAs and that alone was computationally complex using a known model to compare against! We have still but scratched the surface.
Building a core cell always intrigued me as an undergraduate and I was often interested in the bare minimum (DNA-wise) lab manufactured bacterial strains that were used in experiments.