How do you deal with spatial resolution? Whether a part of a tumor is nearby blood vessels seems important information that sequencing is difficult to address.

How do you deal with spatial resolution? Whether a part of a tumor is nearby blood vessels seems important information that sequencing is difficult to address. Other things that come to mind: - Size of cells - Texture / shape of cells - Local microenvironment - Morphology of tissue Combining both seems like a promising step forward (as commenters here have already mentioned).