3 ms·
I'm worried about these treatments for people with autoimmune diseases. One, they might be on immunosuppressants, two, immune activation can then kill you throu
by homero 8y ago
I'm worried about these treatments for people with autoimmune diseases. One, they might be on immunosuppressants, two, immune activation can then kill you through the autoimmune disease.
I have ulcerative colitis and am on immunosuppressants. So I'm more likely to get cancer and can't get that treatment.
- qaq 8y agoOne would imagine they will not be used in these cases
- doctoring 8y agoAt our hospital we routinely use many of these therapies even in patients with a variety of autoimmune conditions. In about a third of patients, they'll have an exacerbation of their underlying autoimmune condition, which fortunately only rarely necessitates cessation of the immunotherapy. One of several studies we reference when we treat these patients: https://www.ncbi.nlm.nih.gov/pubmed?term=27687304 https://www.ncbi.nlm.nih.gov/pubmed?term=27687304 What's interesting (and increasingly being studied) is the higher risk of developing an autoimmune condition after treatment with some of these immunotherapies. The absolute risk doesn't seem to be huge, but it's an interesting window into how these conditions might develop in the first place.
- homero 8y agoThat's good to hear. Would you stop, say Humira before treatment?