In order to get tax breaks from a country you must be incorporated in that country. So, tautologically, any company that would pay these EU taxes must be an EU

In order to get tax breaks from a country you must be incorporated in that country. So, tautologically, any company that would pay these EU taxes must be an EU company. In the most pedantic sense, this cannot affect US companies. However US (and other multinational) companies set up subsidiaries and then funnel money through them to get tax breaks thanks to bilateral double-taxation-avoidance agreements. These would be affected, but they've structured themselves this way intentionally so that their profits are collected in a company headquartered in the EU. (Though it should be noted that headquartering EU operations in an EU country is generally a requirement for dealing with EU consumers without tarrifs and so on, but many multinationals funnel their international money through the EU company). You can't have it both ways. Either you're an EU company which gives you certain tax breaks, or you're a US company that has no tax benefits in the EU for global revenue.