Has your doctor talked about Otezla (aprimelast) or biologics? Otezla inhibits PDE4, an enzyme which regulates pro-inflammatory cytokines, and has the benefit

Has your doctor talked about Otezla (aprimelast) or biologics? Otezla inhibits PDE4, an enzyme which regulates pro-inflammatory cytokines, and has the benefit of being an oral medication; one tablet a day. Biologics such as Humira and Stelara are more potent and even more targeted, but need to be injected. What Otezla and biologics have in common is that they're much more narrowly targeted to the immune pathways of PsA/PsO than older systemic treatments such as prednisolone, methotrexate, cyclosporine, etc.