5 ms·
Naproxen (anti-inflammatory) isn't the kind of thing that you want to be on long-term, if it can be avoided, either. I have just been diagnosed with autoimmune
by mnw21cam 8y ago
Naproxen (anti-inflammatory) isn't the kind of thing that you want to be on long-term, if it can be avoided, either. I have just been diagnosed with autoimmune psoriatic arthritis. I had three months of Naproxen, which made it possible to walk a couple of miles each day, but they were basically handed out as a "Here, this should take down the inflammation, now wait for your specialist appointment."
Having said that, I'm not sure Naproxen is any worse than the Prednisolone (steroid) tablets I'm now on for two months while I wait for the Methotrexate (nasty cytotoxic) to work.
If there's a stem cell treatment on the horizon, I'd love to hear about it.
- olliej 8y agoNaproxen is vastly superior to prednisone. The side effects from prednisone are wretched, and long term use is way worse than the impact of naproxen. I was on nsaids for a decade due to poorly constructed skeleton. I only moved off because I became tolerant to them.
- mnw21cam 8y agoAgreed. I think Predisolone is probably a bit better than Prednisone too. Yes, the side-effects of Naproxen were not as bad, but I'm only on Prednisolone for 8 weeks. I wouldn't want it for longer, given how sick it's making me feel right now. Thing is, it is being way more effective on the first dose than Naproxen ever was.
- pkaye 8y agoNaproxen can restrict blood flow to the kidneys so need to be cautious in the long term.
- olliej 8y agoYeah, but compared to prednisone it's water :) The NSAIDs are all remarkably safe, as opposed to steroids, and the non-steroidal non-NSAIDs (wtf thought it was good to make NSAID mean just a specific group??). I'm on Celebrex, which is much more exciting in its side effect profile, but is still preferable to prednisone :-/
- atombender 8y agoHas your doctor talked about Otezla (aprimelast) or biologics? Otezla inhibits PDE4, an enzyme which regulates pro-inflammatory cytokines, and has the benefit of being an oral medication; one tablet a day. Biologics such as Humira and Stelara are more potent and even more targeted, but need to be injected. What Otezla and biologics have in common is that they're much more narrowly targeted to the immune pathways of PsA/PsO than older systemic treatments such as prednisolone, methotrexate, cyclosporine, etc.
- mnw21cam 8y agoThanks for the info. It looks like I only get Otezla if Methotrexate fails to work, or I pay a lot.
- zdragnar 8y agoYou may want to look into Taltz. It has really helped me, and practically no side effects aside from some injection site reactions. If your insurance won't cover it (mine wouldn't without trying older ones with way worse potential side effects) the drug company offers a program that only requires a $25 copay.