4 ms·

For the record, a large part of anesthesia worldwide is done with that molecule. Potency is not everything, and using sufentanyl in hospital contexts is very mu

by rscho 8y ago

For the record, a large part of anesthesia worldwide is done with that molecule. Potency is not everything, and using sufentanyl in hospital contexts is very much justified. The tablet formula of course makes it far more prone to misuse, though... I can also add that iv remifentanyl is on the market in the US, prescribed routinely, and is much more powerful than even sufentanyl. In fact, so powerful that getting high on it would most certainly kill you, making it pretty much useless to drug users. So again, potency is not everything.

chimeracoder 8y ago
> The tablet formula of course makes it far more prone to misuse, though... The primary danger of fentanyl is accidental use - ie, people consuming lethal doses of fentanyl because their heroin (which is much less potent, by weight) is cut with fentanyl. It's unclear from this article whether that's a risk here, which depends (among other things) on how readily Dsuvia is absorbed through other means.
DanBC 8y ago
> In fact, so powerful that getting high on it would most certainly kill you To be fair, this is what we used to say about fentanyl until recently.
- rscho 8y ago
  The problem is that with high potency, you also get more side effects for the same "painkiller" effect (also depending on absorption velocity). Therefore, using something such as remifentanyl in the mix would almost certainly be counterproductive if you are looking for the "high". It would displace fentanyl, and be more risky. And first of all, it is far more expensive than fentanyl.