There's an adaptation question too for foods in the ancestral environment, not just in the last 10k years. What are the selection pressures? If you make it to a

There's an adaptation question too for foods in the ancestral environment, not just in the last 10k years. What are the selection pressures? If you make it to about 50 as a woman, you're done with even the possibility of reproducing. So all you really need is a tolerance of whatever local food you have until you're that old; if long term exposure messes you up at 60 it doesn't matter. For someone today, wanting to extend their life as long as possible, there is probably a lot in the ancestral / paleo food range you should still avoid, and probably some foods only made possible with technology that provide superior long term outlooks.