I've been reading about various paths from chemotrophic organisms to human-edible food for a long time, mostly as an offshoot of my interest in human deep spac

I've been reading about various paths from chemotrophic organisms to human-edible food for a long time, mostly as an offshoot of my interest in human deep space exploration. Most of the efforts I've read about start with methanotrophs, but it seems like it could be more energetically efficient to start with hydrogen. Starting with hydrogen also simplifies the hardware since you don't need a separate reactor to combine hydrogen and carbon dioxide. The reason to look into chemotrophic pathways is because photosynthesis under artificial lighting is really inefficient, even with modern LED lights. Vertical farming is great for making premium-quality salad greens and herbs, but absurdly expensive and resource-intensive for providing all of a person's food. Food production that starts with chemotrophs and renewable hydrogen instead of phototrophs and renewable lighting has the potential to deliver much more nutrition per-dollar and per-acre, while still delivering many of the benefits touted by vertical farming (low water use, less long-distance transportation of food, using land that is otherwise unsuited for agriculture).