According to the supplementary information in the Jones paper, they processed data using the XDS package. https://strucbio.biologie.uni-konstanz.de/xdswiki/ind

According to the supplementary information in the Jones paper, they processed data using the XDS package. https://strucbio.biologie.uni-konstanz.de/xdswiki/index.php/Main_Page https://strucbio.biologie.uni-konstanz.de/xdswiki/index.php/... Here are some XDS benchmarks: https://bl831.als.lbl.gov/~jamesh/benchmarks/ https://bl831.als.lbl.gov/~jamesh/benchmarks/ It looks like XDS will easily process a data set in well under an hour on any reasonably modern multicore CPU, and within a few minutes on a modern system with 16 or more cores. According to those numbers it looks perfectly usable on a laptop.