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This makes sense. Glucose at above certain levels ruins cells, so Metformin lowers the glucose level. Asking the doc is key, you can't just read an article and
by onetimemanytime 8y ago
This makes sense. Glucose at above certain levels ruins cells, so Metformin lowers the glucose level.
Asking the doc is key, you can't just read an article and try to find 4-5 meds to take each day :)
- cgh 8y agoYou can also eat a very low-carb diet. Restricting your carbs to foods like greens and berries will have the same effect without the need for a prescription. Gluconeogenesis is demand-driven. Of course, in the context of anti-aging, Metformin may have other beneficial effects outside of moderating glucose levels.
- village-idiot 8y agoFasting is also a good idea. It forces your body to kill off marginal cells for food, rather than leaving them to potentially become cancer.
- _Schizotypy 8y agoCan you cite a source please? I would be very interested in reading it
- sushid 8y agoNot the parent but try searching online for fasting and autophagy. There are countless sources regarding this link. Another good recent study is the intestinal stem cell regenerative boost after a 24 hour fast in mice. One might say that the links are still not solid, but we do know that lowering glucose levels might be a good idea (hence the interest in metformin) and fasting/keto certainly achieves that without a drug.
- village-idiot 8y agoI really like the stuff that Mark Sisson writes on fasting[0], because he explains and links all his sources. 0. https://www.marksdailyapple.com/health-benefits-of-intermittent-fasting/ https://www.marksdailyapple.com/health-benefits-of-intermitt...
- BurningFrog 8y agoOh, that's a cute concrete theory I've never heard before. I do fast occasionally, but not as often as I'd wish.
- village-idiot 8y agoIf you want to learn more, the biological process is called “autophagy”.
- onetimemanytime 8y agoYeah, but taking a pill and eating what you want (more or less) is much better
- JamesBarney 8y agoI don't think it's primary effect on lifespan is through glucose regulation. There are other diabetes medications that don't have this same effect. Also see https://www.gwern.net/Longevity#metformin https://www.gwern.net/Longevity#metformin for more info.