3 ms·
Probably that certain base sequences are more likely to occur together than random. If you account for this, it'll help in your compression.
by deugtniet 8y ago
Probably that certain base sequences are more likely to occur together than random. If you account for this, it'll help in your compression.
- pdkl95 8y agoThat's right - the Huffman tree was built based on the base frequency of use, which actually varies depending on what type of organism you're sequencing[1]. [1] https://en.wikipedia.org/wiki/GC-content#Among-genome_variation https://en.wikipedia.org/wiki/GC-content#Among-genome_variat...