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Noob here. Doesn't targeted genetic mutation have an additional step of recognizing the exact gene (or combination of genes or gene properties, whatever the ter
by milansm 8y ago
Noob here. Doesn't targeted genetic mutation have an additional step of recognizing the exact gene (or combination of genes or gene properties, whatever the terminology is) that is needed to be changed in order for the desired outcome to take place? If so, isn't all that fuss about GMO exactly about that additional step with several open questions like:
1. we cannot be sure that the gene we're editing is the one that is responsible for the feature we want (or that it is responsible only for that feature)
2. What are the chances of editing the wrong gene and noticing it?
3. What happens is we edit the wrong gene without noticing it?
- acomjean 8y agoGenerally (I’m learning this stuff too). It’s gene to protein. You have to research what each protein does in the cell. Lots of research is about this. Crispr knock out is about turning off genes and seeing what happens. 2. Crispr has off target effects, they have some tools to help mininize those. It’s hard as some genes have paralogs that produce similar proteins in the same species.