If I'm starting development on a Windows 10 app tomorrow, with no legacy codebase, and I'm going to target only Windows 10, which framework would you suggest? I

If I'm starting development on a Windows 10 app tomorrow, with no legacy codebase, and I'm going to target only Windows 10, which framework would you suggest? I want it to be the best of both worlds: when running on a Surface or other detachable with the keyboard detached, it should have no compromise compared to an iPad Pro app in its UX, with fluid gestures, working well with high PPI screens, and so on. At the same time, when running on a system with keyboard and mouse, it should have no compromise relative to a classic desktop app with all the power users expect, like full multitasking. Which framework provides the best of both worlds? Not UWP, since it doesn't offer full multitasking and is limited in various other ways like sandboxing that I can't opt out of. Is there ANY framework that provides the best of both worlds?