Yes; any framework or tooling that relies on runtime imports (eval is OK, just not eval-from-file) is not going to work with rather a lot of compiled-python pr

Yes; any framework or tooling that relies on runtime imports (eval is OK, just not eval-from-file) is not going to work with rather a lot of compiled-python programs. It's possible to build shims that support "import module if running interpreted python; just point to already-loaded/compiled code (or eval a string, ew, but if you must) if not", but many large projects do not do that. It is likely not too painful to implement/send a PR for though.