Yes, this is valid to point out as a tradeoff. I weight clean markup and "knowing immediately where i am by looking at the code" more heavily in this particula

Yes, this is valid to point out as a tradeoff. I weight clean markup and "knowing immediately where i am by looking at the code" more heavily in this particular balance scale, though -- it's a higher-level concern in some sense. Practically speaking, I'd typically have the markup open side by side with the SASS (or other source CSS) file where "profile-card" was defined in vim, so the lookup process is just moving my eyes across the page.