Safari Content Blocker is pretty great but it's restricted to Safari only. So if you use Reeder, for example, to view articles then ads won't get blocked. As a

Safari Content Blocker is pretty great but it's restricted to Safari only. So if you use Reeder, for example, to view articles then ads won't get blocked. As an additional system-wide layer, I subscribe to Peter Lowe's ad block list with Little Snitch. Now I can block all outbound requests to ad servers system-wide. As much as I like PiHole, I don't think it's a one-stop solution. It's generally easier to manage stuff locally on my system. I think the big advantage is for software that isn't as open (like iOS, tvOS, etc). I find that working in layers instead of trying to find a singular solution is easier to work with and provides more flexibility.