anecdotal, but once, after a 2-week period of cold and antibiotics, followed by 1-week worth constipation and and painful release of bowels, i experienced a ver

anecdotal, but once, after a 2-week period of cold and antibiotics, followed by 1-week worth constipation and and painful release of bowels, i experienced a very vivid depression (anxiety, fear, it's a bad, persistent feeling. NOTHING i did managed to shake it off). I'm a very introspective person in general, and while my brain was telling me it's because 'i'm worthless', i managed to convince myself that something was happening in my digestive system. My first guess was some kind of a laceration (due to constipation) in the colon. I mean, why not? When you are happy, you feel butterflies in your stomach, right? But at that time, everything that 'usually' bring butterflies to my stomach, ended up doing the opposite. That's how i thought about it then. I was also aware we have a lot of neurons in our gut. Note, that, while i made this connection, it was not at all obvious it had anything to do with the gut at all, it all started as a hypothesis. Anyway, I swallowed paracetamol, which is used to treat fever and pain. And the difference was clear as day, the bad feeling stopped. At least for 2 hours. But what happened next cleared me of any doubt that the source is somewhere in my gut. I was waiting in a reclining chair in my car, feeling bad because the effect of paracetamol had subsided. That's when i discovered that 'whether i feel bad or not depends entirely on the angle of the reclining chair i was on'. I tested it, if i raised it to such degree, i will start feeling bad, and if i lower it to such degree, i will stop feeling bad. It was so weird to me. Anyway the bad feeling persisted for like a week after, then i was back to my usual self. However, had i internalized it, I'm sure it would have a long, and destructive, tail.