Even worse! There's quite a fair amount of research indicating that the earlier reports of correlations of the plaques and Alzheimer’s is not causative. In addi

Even worse! There's quite a fair amount of research indicating that the earlier reports of correlations of the plaques and Alzheimer’s is not causative. In addition the older research showing correlation between Alzheimer and amyloid/tau plaques really is coming under more scrutiny (as the PT article points out) as the plaques don't appear to relate to cognitive decline. Though of course, the parent article has some chance of having a correct or partially correct hypothesis as say plaque correlations only appear in a subset of a genetic population and AZ is two distinct disease mechanisms with different etiologies. It's like the issue with statin's... a decent working hypothesis (but barely flushed out past first year grad school research) gets postulated and scooped up by the media. Then drug companies and publicly funded researchers spend billions research interventionist drugs. Often without due diligence on the fundamental scientific hypothesis -- good luck getting a grant on testing that when they hype cycle is full on. Then you're left with an enormous amount of money spent with debatable long term societal effects [1, 2, 3]. I wonder if SV and VC getting more into medicine if these trends will get better or worse. Though it's still possible that there's no way to discover the longer term effect of cholesterol and statins unless you spend a few billion. But surely, there's got to be better ways. 1: https://www.express.co.uk/life-style/health/828448/statins-warning-heart-medicine-fail-harms-health-study-reveals https://www.express.co.uk/life-style/health/828448/statins-w... 2: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513492/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513492/ 3: http://www.statinnation.net/blog/2018/1/8/quzr8nj3k9v23at4fe1k4bwcuvwi91 http://www.statinnation.net/blog/2018/1/8/quzr8nj3k9v23at4fe...