4 ms·

I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology th

I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!

faitswulff 8y ago
Closest I know of is Fierce Biotech https://www.fiercebiotech.com/ https://www.fiercebiotech.com/
- sphix0r 8y ago
  thanks a lot!
rotexo 8y ago
Gene therapy has had some recent successes [0], but it is worth noting that many of the ongoing and recent clinical gene therapy trials don’t necessarily involve genome editing: go to clinicaltrials.gov, search ‘gene therapy’ and get 3741 results. Search ‘CRISPR’ or ‘TALEN’ and get ~21 results. Edit: I should say that most of the gene therapy clinical trials don’t involve genome editing yet. Though it seems to me that, at least for some diseases, viral vectors that deliver DNA to cells without integrating DNA into the host cell genome (where the dna instead persists inside the cells episomally, and is maybe lost from the cells after some number of divisions) will have advantages over integrating vectors/genome editing-based approaches. That way, you don’t have to worry about the off-target effects of genome editing, and you have a treatment that doesn’t result in permanent changes to the genome. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879992/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879992/
djsumdog 8y ago
Lobste.rs is open source and you could potentially spin up an instance of it specific to some topic you're interested in. https://write.narwhal.space/ https://write.narwhal.space/ was an attempt at making an instance for writers, but it seems to have gone into disrepair.
technobabble 8y ago
Sadly, I don't think so. Check your local meetups. Additionally, SynBioBeta has been an ok source for recent biotech news.

faitswulff 8y ago

Closest I know of is Fierce Biotech https://www.fiercebiotech.com/ https://www.fiercebiotech.com/

sphix0r 8y ago
thanks a lot!

rotexo 8y ago

Gene therapy has had some recent successes [0], but it is worth noting that many of the ongoing and recent clinical gene therapy trials don’t necessarily involve genome editing: go to clinicaltrials.gov, search ‘gene therapy’ and get 3741 results. Search ‘CRISPR’ or ‘TALEN’ and get ~21 results. Edit: I should say that most of the gene therapy clinical trials don’t involve genome editing yet. Though it seems to me that, at least for some diseases, viral vectors that deliver DNA to cells without integrating DNA into the host cell genome (where the dna instead persists inside the cells episomally, and is maybe lost from the cells after some number of divisions) will have advantages over integrating vectors/genome editing-based approaches. That way, you don’t have to worry about the off-target effects of genome editing, and you have a treatment that doesn’t result in permanent changes to the genome. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879992/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879992/

djsumdog 8y ago

Lobste.rs is open source and you could potentially spin up an instance of it specific to some topic you're interested in. https://write.narwhal.space/ https://write.narwhal.space/ was an attempt at making an instance for writers, but it seems to have gone into disrepair.

technobabble 8y ago

Sadly, I don't think so. Check your local meetups. Additionally, SynBioBeta has been an ok source for recent biotech news.