Sure, they're both IV abusable, but my point was that for the patients that are still addicted to opioids the more immediate dissolve of the patented formulatio

Sure, they're both IV abusable, but my point was that for the patients that are still addicted to opioids the more immediate dissolve of the patented formulation would make it more preferable to subutex for providers, simply because they know that a patient couldn't take the tablet out of their mouth since it would have dissolved immediately. It's those patients we're trying to get back on track with something better, not the patients we know are able to manage on take-home regimens. > the naltrexone does nothing compared to how strongly bupe itself binds to your receptors. What? First of all, it's naloxone rather than naltrexone that is found in suboxone. Subutex doesn't have either of them. And secondly, it's very, VERY well known that naloxone/naltrexone have far more binding affinity to the mu-opioid receptor (the type that we think causes euphoria/analgesia) compared to any sort of opioid we have on the market (maybe not sufentanyl, but even that I'm fairly certain is weaker affinity). That's exactly why we can use Narcan effectively to combat opioid overdose.