I know what peer review is. And to your point about the demand we make of researchers and the stakes involved, have a read of the Cochrane Collaboration website

I know what peer review is. And to your point about the demand we make of researchers and the stakes involved, have a read of the Cochrane Collaboration website. Most of their conclusions are "no real evidence, need more studies". It's sobering how much is out there that doesn't stand to really demanding analysis.