You can do that on Earth if your thermal vacuum chamber is big enough. They will run accelerated hot/cold cycles while under vacuum to simulate something like 3

You can do that on Earth if your thermal vacuum chamber is big enough. They will run accelerated hot/cold cycles while under vacuum to simulate something like 30 transitions but if the glue in the hole held out through the entire test, there would be no way to find it. That vehicle had been up there since June so it did pretty well for an unreported patch job.