Since you're talking about the Chrome GC I'm going to assume that you're writing code in JS. If that is the case and you have to need such performance that you'

Since you're talking about the Chrome GC I'm going to assume that you're writing code in JS. If that is the case and you have to need such performance that you're having to worry about GC and tacking references then you are probably using the wrong language. Admittedly Web Assembly is pretty new but it sounds like that is your solution, or even asm.js would be worth considering.