9 ms·

Perhaps. Another one is coffee and cigarettes.

• rhinoceraptor 8y ago
  That could be that nicotine causes you to metabolize caffeine quicker.
  • xiphias 8y ago
    It's not nicotine but polycyclic aromatic hydrocarbons of tobacco that induce the CYP1A2 enzyme (which is the most important enzyme for caffeine metabilization).