By contrast, I've been running Octoprint (a 3D print server) full time for over 2 years on a RPi with a 64 GB SD card and I've seen no issues with the SD card o

By contrast, I've been running Octoprint (a 3D print server) full time for over 2 years on a RPi with a 64 GB SD card and I've seen no issues with the SD card or RPi. I've been capturing camera snapshots every 15 seconds. I've only used half of the capacity of the SD card. It's possible that my use of an extra large SD card has allowed the card to write to previously-unused memory cells rather than erase and overwrite memory cells, helping the card last longer. I wonder if anyone has studied that.