>"Double-blinding a trial isn't as big a deal when what you are measuring is not impact by observer bias (tumor size)." Have you ever tried to measure somethin

>"Double-blinding a trial isn't as big a deal when what you are measuring is not impact by observer bias (tumor size)." Have you ever tried to measure something like this and analyze the data? There are so many ways to skew the results... EDIT: That's not even to mention basic stuff like handling the treated rats more carefully so they are less stressed, etc.