Well exactly, what would be a good comparison here? Why mention heavy long-term abuse of MDMA (which is I think very unusual compared to heavy abuse of alcohol)

Well exactly, what would be a good comparison here? Why mention heavy long-term abuse of MDMA (which is I think very unusual compared to heavy abuse of alcohol) in an article about MDMA treatment? The MAPS PTSD protocol involves, if I remember correctly, in all cases under 20 doses of MDMA in the whole life, mostly much less.