I'm British (Northern Irish) and I moved to the US in 2004 on an H1B visa. You are unlikely to have much success applying for roles where you may be competing w

I'm British (Northern Irish) and I moved to the US in 2004 on an H1B visa. You are unlikely to have much success applying for roles where you may be competing with folks who may not need visas. It's a challenge for companies to even get visas and they could attempt to hire you, only to be unable to get a visa. I see two paths other than marrying an American: 1. Join an EU or UK (I guess that might matter soon) company which has a presence in the US and actually sends folks to the US. US companies with an EU presence might be another option. It really depends where you end up in a big company so you have to do your research on how you might end up being transferred. There is no point in joining a pharma company to do work in IT when bioinformatics folks are the ones who have the opportunity to transfer, unless you are prepared to make that move internally as a prerequisite. 2. Do work with a US company in some sort of subcontractor, outsourcing, or supplier relationship. This is how I made my move because I was doing development for the marketing department of a large pharma company. I developed relationships on both side of the pond and they worked out the path to bring me to the US since I had become critical to their work. This requires a lot of luck and legwork and the the arrangement on the other side won't be like an international transfer at a large company. I turned up in Philly alone with two suitcases with all the stuff I was going to bring to start a new life. Both of these approaches need more hustle now than they ever did before, but aren't impossible if you are actually motivated enough, work at your credentials (get a master's degree!) etc. If you are Northern Irish, I think you can still have a shot at the lottery (https://www.uscis.gov/greencard/diversity-visa https://www.uscis.gov/greencard/diversity-visa).