2 ms·
I don't think the root cause(es) of psychosis have really been determined yet. I think it's fair to say that since many drugs induce immediate psychosis, it's u
by meowface 8y ago
I don't think the root cause(es) of psychosis have really been determined yet. I think it's fair to say that since many drugs induce immediate psychosis, it's unlikely that pruned connections are the only cause.
- stochastic_monk 8y agoIt’s pretty clearly D2-like receptors being overexcited, at least as far as cause and effect. Hence psychotic symptoms in stimulant users and a remission of psychosis in schizophrenic patients when on D2-blocking drugs.
- meowface 8y agoD2 receptors are undoubtedly tied to many forms of psychosis, but their being the root cause is not yet proven.
- clankfan 8y agoPsychosis resulting from meth withdrawal has always suggested to me that it is an under-connected problem because presumably what happens during withdrawal is widespread "disconnection" resulting from a large decrease in synaptic sensitivity (caused by a flood of neurotransmitter, meth) and a steep drop in neurotransmitter activity once the meth is gone.
- tcj_phx 8y agoStimulants shred the cells' mitochondria. Psychosis is a metabolic problem.