Also, this was done on cell lines in vitro, only one of which was derived from a non-diseased human retinal epithelium (ARPE-19). Cell lines have undergone gene

Also, this was done on cell lines in vitro, only one of which was derived from a non-diseased human retinal epithelium (ARPE-19). Cell lines have undergone genetic change that allows them to replicate indefinitely, so they are fundamentally different from normal cells. I presume that they used a laser because they anticipated that it would potentially take years to see a result from a non-coherent blue light source, far exceeding their available funding, patience, and ability to keep uncontaminated cell cultures going. Applying a blue laser with unknown irradiance to a retinal cell line from a single human genetic source in vitro is very, very far from proving a link between blue light and diseases such as macular degeneration and RP. All this demonstrates is that coherent blue light is capable, under certain circumstances, of interacting with retinal to produce cell damage. Any relationship to human disease on the basis of this paper is pure speculation. Advising people to wear "blue blocker" sunglasses or avoid cellphone screens (or take Vitamin E!) is pure fantasy made up by the scientific press to sell your retinas.