There are startups in the midwest, but it's very hard to get funding here: Exec teams have to spend a lot of time traveling to raise money. Still, there are sec

There are startups in the midwest, but it's very hard to get funding here: Exec teams have to spend a lot of time traveling to raise money. Still, there are sectors where the midwest is a clear competitive advantage: You can build a biotech startup working on agriculture in California, but if you need to hire crop scientists and test equipment in farms, you are better off in a midwestern metro, 45 minutes away from large corn and soybean operations. You might want a small office in Boston or San Francisco too though, just to cut exec travel to see investors.