4 ms·
It might (completely guessing here) also mean that lungs that wouldn't be suitable for normal transplant due to health or condition, might be suitable to be use
by theBobBob 8y ago
It might (completely guessing here) also mean that lungs that wouldn't be suitable for normal transplant due to health or condition, might be suitable to be used in this way.
- Brakenshire 8y agoI wonder how much this process reverses the age of the lungs, if you take the lungs of an 80 year old, wash them, reseed them and put them in a 20 year old, what’s the result?
- biofox 8y agoI don't work in this area, but ECM scaffolds undergo significant change with age. Crosslinks and age-related remodelling degrade the mechanical properties of the scaffold and interfere with normal cell migration and differentiation. You would want to start with a healthy organ before decellularising and reseeding.
- improbable22 8y agoBut perhaps not quite as critical as for current transplants? At least that's my uneducated guess... anyone know?
- thefounder 8y agoIf that would work I guess people would like to "refresh" their organs anyway from time to time to avoid failure.
- dmurray 8y agoYes, though I would expect the risk of complications from this procedure will outweigh the benefit for healthy patients for many years after it becomes a "routine" operation for those with lung disease.
- kls 8y agoWeird thought what if a 20'something put cells in a bank and had organs generated from them later in life.