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In this case it also relies on the resistant cancer cells having altered metabolic pathways compared to your average cancer. It's not an universally applicable

In this case it also relies on the resistant cancer cells having altered metabolic pathways compared to your average cancer. It's not an universally applicable strategy. Remember, fasting didn't work out so well for Jobs.

sandworm101 8y ago
Each cancer is different and might respond to different treatments. I was speaking very generally. This paticular cancer reacts because of its unique properties, but the principal may work on others too.
melling 8y ago
Perhaps it should be tried with regular treatments? https://www.scientificamerican.com/article/fasting-might-boost-chemo/ https://www.scientificamerican.com/article/fasting-might-boo...
eganist 8y ago
He also made himself a fruitarian, so the stress on his body was from a lot more than just fasting. This same diet landed Ashton Kutcher in the hospital when he tried to go method for Jobs.
- akuji1993 8y ago
  "Hm, this guy died and one highly likely reason was his diet. In order to play him correctly, I'm gonna try that diet too."
  - SaulOfTheJungle 8y ago
    Ashton Kutcher is not diagnosed with pancreatic cancer.
- ojosilva 8y ago
  Jobs was a fruitarian in the 80s or earlier, back when he named his company "Apple". AFAIK he was neither fasting or being a fruitarian to fight his cancer, but overall he was a finicky eater all his life, a (sometimes lax) vegetarian with bouts that resembled a true eating disorder.
  - macintux 8y ago
    I don't have a source, but I recall reading that friends of his desperately tried to convince him to undergo "real" treatment for his cancer instead of relying on alternative medicine, so apparently he did try other options early on.
    - ojosilva 8y ago
      Here's a good compilation of his unorthodox eating habits: https://www.psychologytoday.com/us/blog/naughty-nutrition/201201/ivegetarian-the-high-fructose-diet-steve-jobs https://www.psychologytoday.com/us/blog/naughty-nutrition/20...
- deleted 8y ago
  [deleted]
sleavey 8y ago
Didn't he only start after the diagnosis? Precancerous cells stand a better chance of being starved with fasting than cancerous cells. By the time the cell is cancerous it has built multiple metabolic pathways to power itself, making it more difficult to kill.
morsma 8y ago
As far as I understand it, then Jobs was doing juice fasts which is probably the worst thing one can do in the presence of cancer.
- madeuptempacct 8y ago
  Why is it the worst thing you can do? It's funny - it's so easy to believe in conspiracy theories but then Shaolin monks and Steve Jobs die of cancer, and suddenly all of that goes out of the window. (Unless you make up another theory, but that's getting too convoluted)
  - logfromblammo 8y ago
    As a guess, I'd say it's because the glucose can be used by the cancer directly as an energy source, and that the fructose can either be metabolized in the tumor directly as an adaptation, or it ties up resources elsewhere in the body that could have been better used to fight the cancer. The lack of protein or fat in the juice means that it cannot help the rest of the body rebuild itself as the tumor is sucking up all available resources. Shipments of essential fats or amino acids are being hijacked by piratical cancer cells, and never reach their intended destinations. If there were an oversupply, some might still get through.
- Shorel 8y ago
  Because of the high sugar content?
Shorel 8y ago
I think his particular way of fasting could have been a factor for the apparition of his cancer. It seems that the best parallel we can do is cancer == DNA "software" bugs. Software debugging is a complex art and what works in one case definitely doesn't work in all cases.

sandworm101 8y ago

Each cancer is different and might respond to different treatments. I was speaking very generally. This paticular cancer reacts because of its unique properties, but the principal may work on others too.

melling 8y ago

Perhaps it should be tried with regular treatments? https://www.scientificamerican.com/article/fasting-might-boost-chemo/ https://www.scientificamerican.com/article/fasting-might-boo...

eganist 8y ago

He also made himself a fruitarian, so the stress on his body was from a lot more than just fasting. This same diet landed Ashton Kutcher in the hospital when he tried to go method for Jobs.

akuji1993 8y ago
"Hm, this guy died and one highly likely reason was his diet. In order to play him correctly, I'm gonna try that diet too."
- SaulOfTheJungle 8y ago
  Ashton Kutcher is not diagnosed with pancreatic cancer.
ojosilva 8y ago
Jobs was a fruitarian in the 80s or earlier, back when he named his company "Apple". AFAIK he was neither fasting or being a fruitarian to fight his cancer, but overall he was a finicky eater all his life, a (sometimes lax) vegetarian with bouts that resembled a true eating disorder.
- macintux 8y ago
  I don't have a source, but I recall reading that friends of his desperately tried to convince him to undergo "real" treatment for his cancer instead of relying on alternative medicine, so apparently he did try other options early on.
  - ojosilva 8y ago
    Here's a good compilation of his unorthodox eating habits: https://www.psychologytoday.com/us/blog/naughty-nutrition/201201/ivegetarian-the-high-fructose-diet-steve-jobs https://www.psychologytoday.com/us/blog/naughty-nutrition/20...
deleted 8y ago
[deleted]

sleavey 8y ago

Didn't he only start after the diagnosis? Precancerous cells stand a better chance of being starved with fasting than cancerous cells. By the time the cell is cancerous it has built multiple metabolic pathways to power itself, making it more difficult to kill.

morsma 8y ago

As far as I understand it, then Jobs was doing juice fasts which is probably the worst thing one can do in the presence of cancer.

madeuptempacct 8y ago
Why is it the worst thing you can do? It's funny - it's so easy to believe in conspiracy theories but then Shaolin monks and Steve Jobs die of cancer, and suddenly all of that goes out of the window. (Unless you make up another theory, but that's getting too convoluted)
- logfromblammo 8y ago
  As a guess, I'd say it's because the glucose can be used by the cancer directly as an energy source, and that the fructose can either be metabolized in the tumor directly as an adaptation, or it ties up resources elsewhere in the body that could have been better used to fight the cancer. The lack of protein or fat in the juice means that it cannot help the rest of the body rebuild itself as the tumor is sucking up all available resources. Shipments of essential fats or amino acids are being hijacked by piratical cancer cells, and never reach their intended destinations. If there were an oversupply, some might still get through.
Shorel 8y ago
Because of the high sugar content?

Shorel 8y ago

I think his particular way of fasting could have been a factor for the apparition of his cancer. It seems that the best parallel we can do is cancer == DNA "software" bugs. Software debugging is a complex art and what works in one case definitely doesn't work in all cases.