No one else has mentioned this, but have you considered upgrading your class of service to premium economy or business (if possible)? I find that my baseline an

No one else has mentioned this, but have you considered upgrading your class of service to premium economy or business (if possible)? I find that my baseline anxiety is far higher after dealing with boarding procedures, jockeying for overhead space, and cramming into a tiny middle seat with my knees touching the seat in front of me than when coddled in first class. The entire pre-flight experience/lack of personal space is (for me) so anxiety provoking that calming myself down for the flight is difficult. It's an expensive fix, but maybe worth exploring if you're flying infrequently. Also worth noting that I'm a 6'2", 220lb person, so YMMV regarding necessary personal space. I also had the luck with learning about flight dynamics, airplanes, and how most unpleasant sensations during flight are well within operational parameters for an aircraft.